STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMC4Transmembrane channel-like protein. (736 aa)    
Predicted Functional Partners:
MBOAT7
Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family.
 
    
 0.743
DUS2
Dihydrouridine synthase 2.
   
  
 0.711
COPRS
Coordinator of PRMT5 and differentiation stimulator.
      
 0.691
PAXBP1
PAX3 and PAX7 binding protein 1.
      
 0.602
COMTD1
Catechol-O-methyltransferase domain containing 1.
      
 0.598
DISP2
Dispatched RND transporter family member 2.
      
 0.537
MDN1
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
      
 0.526
CAMK1G
Calcium/calmodulin dependent protein kinase IG.
      
 0.526
TBC1D12
TBC1 domain family member 12.
      
 0.512
TM6SF2
Transmembrane 6 superfamily member 2.
   
  
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.