STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHAC2Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (184 aa)    
Predicted Functional Partners:
DNAJC21
DnaJ heat shock protein family (Hsp40) member C21.
 
 
    0.716
PLAAT1
Phospholipase A and acyltransferase 1.
      
 0.712
RWDD1
RWD domain containing 1.
   
  
 0.595
MINDY3
MINDY lysine 48 deubiquitinase 3.
      
 0.563
ZNF428
Zinc finger protein 428.
      
 0.559
GORASP1
Golgi reassembly stacking protein 1.
   
  
 0.524
CLUAP1
Clusterin associated protein 1.
   
  
 0.520
CCDC97
Coiled-coil domain containing 97.
      
 0.519
UBL7
Ubiquitin like 7.
      
 0.519
ASB3
Uncharacterized protein.
   
  
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.