STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF5Rap guanine nucleotide exchange factor 5. (884 aa)    
Predicted Functional Partners:
RRAS
RAS related.
    
 0.949
MRAS
Muscle RAS oncogene homolog.
    
 0.934
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.923
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.923
RRAS2
RAS related 2.
    
 0.917
NRAS
Uncharacterized protein.
    
 0.912
HRAS
Uncharacterized protein.
    
 0.912
ADGRG2
Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family.
      
 0.740
CLCN6
Chloride channel protein.
      
 0.677
HSD11B1
Hydroxysteroid 11-beta dehydrogenase 1.
      
 0.572
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.