STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPHA5EPH receptor A5. (978 aa)    
Predicted Functional Partners:
RASA1
RAS p21 protein activator 1.
   
 0.911
ABL1
Tyrosine-protein kinase.
   
0.909
NGEF
Neuronal guanine nucleotide exchange factor.
    
 0.908
EFNA5
Ephrin A5; Belongs to the ephrin family.
   
 0.902
EFNA1
Ephrin A1; Belongs to the ephrin family.
   
 0.843
EFNA3
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
   
 0.801
EFNB1
Ephrin B1.
   
 0.723
EFNB2
Ephrin B2; Belongs to the ephrin family.
   
 0.718
EFNA4
ADAM metallopeptidase domain 15; Belongs to the ephrin family.
   
  0.664
SH3BP5L
SH3 binding domain protein 5 like.
    
 
 0.603
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.