STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2351 aa)    
Predicted Functional Partners:
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
0.873
SPTA1
Spectrin alpha, erythrocytic 1.
   
0.828
SPTBN2
Spectrin beta chain; Belongs to the spectrin family.
  
0.805
ADD2
Adducin 2.
   
 
 0.625
ADD3
Adducin 3.
   
 
 0.548
ADD1
Adducin 1.
   
 
 0.537
SORBS3
Sorbin and SH3 domain containing 3.
   
  
 0.530
ANK1
Ankyrin 1.
   
 
 0.509
CCDC170
Coiled-coil domain containing 170.
    
 
 0.495
DMTN
Dematin actin binding protein.
   
 
 0.493
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.