STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2351 aa)    
Predicted Functional Partners:
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
0.891
SPTA1
Spectrin alpha, erythrocytic 1.
   
0.796
ANK1
Ankyrin 1.
   
 
 0.643
NAPA
NSF attachment protein alpha.
   
 
 0.589
ANK3
Ankyrin 3.
   
 
 0.578
CCDC170
Coiled-coil domain containing 170.
    
 
 0.571
GIT1
GIT ArfGAP 1.
     
 0.569
ANK2
Ankyrin 2.
   
 
 0.563
KDELR2
ER lumen protein-retaining receptor.
   
 
 0.544
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.537
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.