STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STK31Serine/threonine kinase 31. (1018 aa)    
Predicted Functional Partners:
PCNX1
Pecanex 1.
      
 0.701
CAPZA3
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
  
 0.669
SMC1B
Structural maintenance of chromosomes protein.
   
  
 0.650
TDRKH
Tudor and KH domain containing.
   
  
 0.607
GPR83
Probable G-protein coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor; Belongs to the G-protein coupled receptor 1 family.
     
  0.600
RNF17
Ring finger protein 17.
   
  
 0.589
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
    
   0.570
NKAIN4
Sodium/potassium transporting ATPase interacting 4.
   
  
 0.558
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
   
  
 0.552
SPAG6
Sperm associated antigen 6.
   
  
 0.552
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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