STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS11ATransmembrane protease serine; Belongs to the peptidase S1 family. (424 aa)    
Predicted Functional Partners:
TMPRSS4
Transmembrane serine protease 4; Belongs to the peptidase S1 family.
  
 
0.684
CTSL3
Uncharacterized protein; Belongs to the peptidase C1 family.
   
 
 0.637
ACE2
Angiotensin-converting enzyme.
    
 0.637
LOC102156614
Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.
     
 0.636
TMPRSS2
Uncharacterized protein.
      
 0.607
WDR86
WD repeat domain 86.
      
 0.582
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
     
 0.561
PDCL2
Phosducin like 2.
      
 0.553
SERPINB7
Serpin family B member 7; Belongs to the serpin family.
   
 0.531
SERPINB11
Serpin family B member 11; Belongs to the serpin family.
   
 0.531
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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