STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTL7AActin like 7A; Belongs to the actin family. (476 aa)    
Predicted Functional Partners:
AFAP1
Actin filament associated protein 1.
   
 
 0.731
CAPZA3
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.660
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 
 0.569
ABITRAM
Actin binding transcription modulator.
    
 
 0.562
CTNNAL1
Catenin alpha like 1.
    
 
 0.531
MYL1
Myosin light chain 1.
   
 
 0.528
PTGR1
Prostaglandin reductase 1.
      
 0.520
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.517
ACTR10
Actin related protein 10; Belongs to the actin family.
   
 
0.511
ARL10
ADP ribosylation factor like GTPase 10.
  
 
 0.508
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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