STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS11FTransmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)    
Predicted Functional Partners:
TMPRSS4
Transmembrane serine protease 4; Belongs to the peptidase S1 family.
  
0.781
HPN
Hepsin; Belongs to the peptidase S1 family.
  
 
 
0.660
ENSCAFP00000058636
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
  
  0.613
TSPAN7
Tetraspanin.
     
 0.604
ANKRD22
Ankyrin repeat domain 22.
    
 
 0.603
KLK1
Peptidase S1 domain-containing protein.
  
 
   0.557
PSMA5
Proteasome subunit alpha type.
      
 0.533
ARMC9
Armadillo repeat containing 9.
      
 0.525
F7
Coagulation factor X.
  
 
0.498
KLK2
Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known.
  
 
  
0.486
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.