LOC482175 protein (Canis lupus familiaris) - STRING interaction network

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Score

LOC482175

Transmembrane protease serine; Belongs to the peptidase S1 family. (416 aa)

Predicted Functional Partners:

TMPRSS4

0.560

PRSS58

0.518

ACE2

0.428

KLK1

0.406

TOP3B

0.403

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	KLK1	ENSCAFP00000041771	ENSCAFP00000054379	Angiotensin-converting enzyme.	Peptidase S1 domain-containing protein.	0.752
ACE2	LOC482175	ENSCAFP00000041771	ENSCAFP00000004156	Angiotensin-converting enzyme.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.428
ACE2	TMPRSS4	ENSCAFP00000041771	ENSCAFP00000058627	Angiotensin-converting enzyme.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.683
KLK1	ACE2	ENSCAFP00000054379	ENSCAFP00000041771	Peptidase S1 domain-containing protein.	Angiotensin-converting enzyme.	0.752
KLK1	LOC482175	ENSCAFP00000054379	ENSCAFP00000004156	Peptidase S1 domain-containing protein.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.406
LOC482175	ACE2	ENSCAFP00000004156	ENSCAFP00000041771	Transmembrane protease serine; Belongs to the peptidase S1 family.	Angiotensin-converting enzyme.	0.428
LOC482175	KLK1	ENSCAFP00000004156	ENSCAFP00000054379	Transmembrane protease serine; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein.	0.406
LOC482175	PRSS58	ENSCAFP00000004156	ENSCAFP00000005689	Transmembrane protease serine; Belongs to the peptidase S1 family.	Serine protease 58; Belongs to the peptidase S1 family.	0.518
LOC482175	TMPRSS4	ENSCAFP00000004156	ENSCAFP00000058627	Transmembrane protease serine; Belongs to the peptidase S1 family.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.560
LOC482175	TOP3B	ENSCAFP00000004156	ENSCAFP00000022795	Transmembrane protease serine; Belongs to the peptidase S1 family.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.403
PRSS58	LOC482175	ENSCAFP00000005689	ENSCAFP00000004156	Serine protease 58; Belongs to the peptidase S1 family.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.518
TMPRSS4	ACE2	ENSCAFP00000058627	ENSCAFP00000041771	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	Angiotensin-converting enzyme.	0.683
TMPRSS4	LOC482175	ENSCAFP00000058627	ENSCAFP00000004156	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.560
TMPRSS4	TOP3B	ENSCAFP00000058627	ENSCAFP00000022795	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.543
TOP3B	LOC482175	ENSCAFP00000022795	ENSCAFP00000004156	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.403
TOP3B	TMPRSS4	ENSCAFP00000022795	ENSCAFP00000058627	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.543