STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL3Oxysterol-binding protein; Belongs to the OSBP family. (887 aa)    
Predicted Functional Partners:
VAPB
VAMP associated protein B and C.
    
 
 0.853
HNRNPA3
Heterogeneous nuclear ribonucleoprotein A3.
      
 0.851
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
      
 0.826
OSBPL6
Oxysterol-binding protein; Belongs to the OSBP family.
    
   0.725
NFE2L3
Nuclear factor, erythroid 2 like 3.
      
 0.708
PDE11A
Phosphodiesterase.
      
 0.704
VAPA
VAMP associated protein A.
    
 
 0.701
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).
   
  
 0.693
CASP9
Caspase 9; Belongs to the peptidase C14A family.
      
 0.692
NFE2L2
Nuclear factor, erythroid 2 like 2.
      
 0.659
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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