STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (250 aa)    
Predicted Functional Partners:
CSN3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.
   
  
 0.981
LALBA
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.969
CSN1S1
Casein alpha s1.
   
  
 0.963
BTN1A1
Butyrophilin subfamily 1 member A1.
   
  
 0.845
LOC100856000
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
      
 0.829
PRLR
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
   
  
 0.780
LTF
Uncharacterized protein; Belongs to the transferrin family.
   
  
 0.774
STAT5A
Signal transducer and activator of transcription.
   
  
 0.739
H9GW77_CANLF
Uncharacterized protein.
   
  
 0.718
PRL
Prolactin.
      
 0.698
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.