STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSN3Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family. (185 aa)    
Predicted Functional Partners:
CSN2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
   
  
 0.992
CSN1S1
Casein alpha s1.
   
 
 0.991
LOC100856000
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
  
 0.955
LALBA
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.954
LOC491263
Beta-lactoglobulin-2; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family.
   
 
 0.830
KCNN4
Potassium calcium-activated channel subfamily N member 4.
      
 0.611
LTF
Uncharacterized protein; Belongs to the transferrin family.
      
 0.597
COPS7A
COP9 signalosome subunit 7A.
    
 
 0.574
BTN1A1
Butyrophilin subfamily 1 member A1.
   
 
 0.562
LYZ
Lysozyme C, spleen isozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.548
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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