LOC100685589 protein (Canis lupus familiaris)

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LOC100685589

DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (418 aa)

Predicted Functional Partners:

XRCC5

0.852

XRCC6

0.852

TENT4A

0.706

AFF3

0.703

PCNA

0.648

MUTYH

0.625

POLH

0.619

PNLIP

0.612

LIG4

0.610

LIG1

0.591

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFF3	LIG1	ENSCAFP00000052865	ENSCAFP00000066742	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	DNA ligase.	0.414
AFF3	LIG4	ENSCAFP00000052865	ENSCAFP00000009027	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	DNA ligase.	0.511
AFF3	LOC100685589	ENSCAFP00000052865	ENSCAFP00000004275	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.703
AFF3	PCNA	ENSCAFP00000052865	ENSCAFP00000009045	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.952
AFF3	POLH	ENSCAFP00000052865	ENSCAFP00000002810	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	DNA polymerase eta.	0.983
AFF3	TENT4A	ENSCAFP00000052865	ENSCAFP00000015164	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Terminal nucleotidyltransferase 4A.	0.424
LIG1	AFF3	ENSCAFP00000066742	ENSCAFP00000052865	DNA ligase.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.414
LIG1	LIG4	ENSCAFP00000066742	ENSCAFP00000009027	DNA ligase.	DNA ligase.	0.740
LIG1	LOC100685589	ENSCAFP00000066742	ENSCAFP00000004275	DNA ligase.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.591
LIG1	PCNA	ENSCAFP00000066742	ENSCAFP00000009045	DNA ligase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.994
LIG1	POLH	ENSCAFP00000066742	ENSCAFP00000002810	DNA ligase.	DNA polymerase eta.	0.492
LIG1	XRCC5	ENSCAFP00000066742	ENSCAFP00000038467	DNA ligase.	X-ray repair cross complementing 5.	0.737
LIG1	XRCC6	ENSCAFP00000066742	ENSCAFP00000058107	DNA ligase.	X-ray repair cross complementing 6.	0.701
LIG4	AFF3	ENSCAFP00000009027	ENSCAFP00000052865	DNA ligase.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.511
LIG4	LIG1	ENSCAFP00000009027	ENSCAFP00000066742	DNA ligase.	DNA ligase.	0.740
LIG4	LOC100685589	ENSCAFP00000009027	ENSCAFP00000004275	DNA ligase.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.610
LIG4	PCNA	ENSCAFP00000009027	ENSCAFP00000009045	DNA ligase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.766
LIG4	XRCC5	ENSCAFP00000009027	ENSCAFP00000038467	DNA ligase.	X-ray repair cross complementing 5.	0.973
LIG4	XRCC6	ENSCAFP00000009027	ENSCAFP00000058107	DNA ligase.	X-ray repair cross complementing 6.	0.975
LOC100685589	AFF3	ENSCAFP00000004275	ENSCAFP00000052865	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.703

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