AMTN protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AMTN

Amelotin. (211 aa)

Predicted Functional Partners:

ENAM

0.957

AMBN

0.941

ODAM

0.919

KLK4

0.854

AMELX

0.852

MMP20

0.835

MEPE

0.813

DMP1

0.701

DSG1

0.688

FAM20A-2

0.673

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBN	AMELX	ENSCAFP00000004304	ENSCAFP00000017046	Ameloblastin.	Amelogenin X isoform.	0.919
AMBN	AMTN	ENSCAFP00000004304	ENSCAFP00000004282	Ameloblastin.	Amelotin.	0.941
AMBN	DMP1	ENSCAFP00000004304	ENSCAFP00000014035	Ameloblastin.	Dentin matrix acidic phosphoprotein 1.	0.438
AMBN	ENAM	ENSCAFP00000004304	ENSCAFP00000004311	Ameloblastin.	Enamelin.	0.970
AMBN	FAM20A-2	ENSCAFP00000004304	ENSCAFP00000056718	Ameloblastin.	Fam20C domain-containing protein.	0.706
AMBN	KLK4	ENSCAFP00000004304	ENSCAFP00000052647	Ameloblastin.	Kallikrein related peptidase 4; Belongs to the peptidase S1 family.	0.901
AMBN	MEPE	ENSCAFP00000004304	ENSCAFP00000064797	Ameloblastin.	Matrix extracellular phosphoglycoprotein.	0.476
AMBN	MMP20	ENSCAFP00000004304	ENSCAFP00000022211	Ameloblastin.	Matrix metallopeptidase 20.	0.820
AMBN	ODAM	ENSCAFP00000004304	ENSCAFP00000004263	Ameloblastin.	Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.	0.838
AMELX	AMBN	ENSCAFP00000017046	ENSCAFP00000004304	Amelogenin X isoform.	Ameloblastin.	0.919
AMELX	AMTN	ENSCAFP00000017046	ENSCAFP00000004282	Amelogenin X isoform.	Amelotin.	0.852
AMELX	DMP1	ENSCAFP00000017046	ENSCAFP00000014035	Amelogenin X isoform.	Dentin matrix acidic phosphoprotein 1.	0.586
AMELX	ENAM	ENSCAFP00000017046	ENSCAFP00000004311	Amelogenin X isoform.	Enamelin.	0.916
AMELX	FAM20A-2	ENSCAFP00000017046	ENSCAFP00000056718	Amelogenin X isoform.	Fam20C domain-containing protein.	0.715
AMELX	KLK4	ENSCAFP00000017046	ENSCAFP00000052647	Amelogenin X isoform.	Kallikrein related peptidase 4; Belongs to the peptidase S1 family.	0.853
AMELX	MEPE	ENSCAFP00000017046	ENSCAFP00000064797	Amelogenin X isoform.	Matrix extracellular phosphoglycoprotein.	0.452
AMELX	MMP20	ENSCAFP00000017046	ENSCAFP00000022211	Amelogenin X isoform.	Matrix metallopeptidase 20.	0.866
AMELX	ODAM	ENSCAFP00000017046	ENSCAFP00000004263	Amelogenin X isoform.	Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.	0.826
AMTN	AMBN	ENSCAFP00000004282	ENSCAFP00000004304	Amelotin.	Ameloblastin.	0.941
AMTN	AMELX	ENSCAFP00000004282	ENSCAFP00000017046	Amelotin.	Amelogenin X isoform.	0.852