STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PNPT1Polyribonucleotide nucleotidyltransferase 1. (763 aa)    
Predicted Functional Partners:
SUPV3L1
Suv3 like RNA helicase.
   
 0.970
SEMA6B
Semaphorin 6B; Belongs to the semaphorin family.
   
    0.967
PMPCB
Peptidase, mitochondrial processing beta subunit; Belongs to the peptidase M16 family.
  
 
 0.884
PMPCA
Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family.
  
 
 0.819
EXOSC10
Exosome component 10.
   
 
 0.810
DIS3
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.
   
 
 0.788
ALDH1A1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
  
 0.784
TSFM
Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
 
 0.751
IMP3
IMP U3 small nucleolar ribonucleoprotein 3.
  
  
 0.751
EXOSC4
Exosome component 4.
   
 
 0.747
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.