STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEBP1AE binding protein 1. (855 aa)    
Predicted Functional Partners:
SYS1
Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family.
      
 0.694
TP53TG5
TP53 target 5.
      
 0.650
DTNBP1
Dystrobrevin binding protein 1.
      
 0.591
EDNRA
Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity).
   
  
 0.554
POLD2
DNA polymerase delta 2, accessory subunit.
      
 0.533
ZNF469
Uncharacterized protein.
      
 0.531
FMOD
Fibromodulin.
   
  
 0.527
CFAP61
Cilia and flagella associated protein 61.
      
 0.521
LRRTM4
Leucine rich repeat transmembrane neuronal 4.
      
 0.502
PRDM5
Zinc finger protein.
      
 0.501
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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