GCK protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

GCK

Phosphotransferase. (226 aa)

Predicted Functional Partners:

GCKR

0.977

G6PC2

0.976

HK2

0.962

G6PC3

0.961

G6PC

0.959

ADPGK

0.948

G6PD

0.935

TKT

0.932

H6PD

0.931

PGM1

0.911

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADPGK	G6PC	ENSCAFP00000026156	ENSCAFP00000021606	ADP dependent glucokinase.	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	0.778
ADPGK	G6PC2	ENSCAFP00000026156	ENSCAFP00000017476	ADP dependent glucokinase.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.885
ADPGK	G6PC3	ENSCAFP00000026156	ENSCAFP00000021204	ADP dependent glucokinase.	Glucose-6-phosphatase catalytic subunit 3.	0.885
ADPGK	G6PD	ENSCAFP00000026156	ENSCAFP00000028993	ADP dependent glucokinase.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.898
ADPGK	GCK	ENSCAFP00000026156	ENSCAFP00000004364	ADP dependent glucokinase.	Phosphotransferase.	0.948
ADPGK	H6PD	ENSCAFP00000026156	ENSCAFP00000053617	ADP dependent glucokinase.	Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.	0.883
ADPGK	HK2	ENSCAFP00000026156	ENSCAFP00000012208	ADP dependent glucokinase.	Hexokinase 2.	0.904
ADPGK	PGM1	ENSCAFP00000026156	ENSCAFP00000057497	ADP dependent glucokinase.	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.	0.890
ADPGK	TKT	ENSCAFP00000026156	ENSCAFP00000044643	ADP dependent glucokinase.	Transketolase.	0.888
G6PC	ADPGK	ENSCAFP00000021606	ENSCAFP00000026156	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	ADP dependent glucokinase.	0.778
G6PC	G6PC2	ENSCAFP00000021606	ENSCAFP00000017476	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.769
G6PC	G6PC3	ENSCAFP00000021606	ENSCAFP00000021204	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Glucose-6-phosphatase catalytic subunit 3.	0.769
G6PC	G6PD	ENSCAFP00000021606	ENSCAFP00000028993	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.889
G6PC	GCK	ENSCAFP00000021606	ENSCAFP00000004364	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Phosphotransferase.	0.959
G6PC	GCKR	ENSCAFP00000021606	ENSCAFP00000007696	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Uncharacterized protein.	0.404
G6PC	H6PD	ENSCAFP00000021606	ENSCAFP00000053617	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.	0.810
G6PC	HK2	ENSCAFP00000021606	ENSCAFP00000012208	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Hexokinase 2.	0.892
G6PC	PGM1	ENSCAFP00000021606	ENSCAFP00000057497	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.	0.851
G6PC	TKT	ENSCAFP00000021606	ENSCAFP00000044643	Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity).	Transketolase.	0.773
G6PC2	ADPGK	ENSCAFP00000017476	ENSCAFP00000026156	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	ADP dependent glucokinase.	0.885