STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXA4Homeobox A4. (317 aa)    
Predicted Functional Partners:
HOXA3
Homeobox A3.
   
  
0.727
KLRB1
Killer cell lectin like receptor B1.
      
 0.627
HOXA2
Homeobox A2.
   
 
0.545
POU6F1
POU domain protein.
    
 
 0.503
RCOR3
REST corepressor 3.
    
 
 0.493
DGKK
Diacylglycerol kinase.
      
 0.489
EIF2D
Eukaryotic translation initiation factor 2D.
      
 0.469
IRX6
Iroquois homeobox 6.
   
 
 0.463
PBX1
PBX homeobox 1.
   
 
 0.462
MYCBPAP
MYCBP associated protein.
   
  
 0.435
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.