STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXA13Homeobox A13. (389 aa)    
Predicted Functional Partners:
MEIS2
Meis homeobox 2.
    
 
 0.652
MEIS1
Meis homeobox 1.
    
 
 0.642
SALL3
Spalt like transcription factor 3.
   
 
 0.638
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.584
PBX1
PBX homeobox 1.
    
 
 0.539
DGKK
Diacylglycerol kinase.
   
  
 0.514
EMX2
Empty spiracles homeobox 2.
    
 
 0.499
DHH
Desert hedgehog signaling molecule.
      
 0.497
SALL1
Spalt like transcription factor 1.
   
 
 0.490
FGF8
Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells (By similarity).
      
 0.471
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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