| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHUK | NFKB1 | ENSCAFP00000014093 | ENSCAFP00000056706 | Component of inhibitor of nuclear factor kappa B kinase complex. | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | 0.997 |
| CHUK | NFKB2 | ENSCAFP00000014093 | ENSCAFP00000014918 | Component of inhibitor of nuclear factor kappa B kinase complex. | Nuclear factor kappa B subunit 2. | 0.997 |
| CHUK | NFKBIA | ENSCAFP00000014093 | ENSCAFP00000019772 | Component of inhibitor of nuclear factor kappa B kinase complex. | NFKB inhibitor alpha. | 0.998 |
| CHUK | NFKBIB | ENSCAFP00000014093 | ENSCAFP00000042141 | Component of inhibitor of nuclear factor kappa B kinase complex. | NFKB inhibitor beta. | 0.998 |
| CHUK | NFKBIE | ENSCAFP00000014093 | ENSCAFP00000002917 | Component of inhibitor of nuclear factor kappa B kinase complex. | ANK_REP_REGION domain-containing protein. | 0.968 |
| CHUK | REL | ENSCAFP00000014093 | ENSCAFP00000004425 | Component of inhibitor of nuclear factor kappa B kinase complex. | REL proto-oncogene, NF-kB subunit. | 0.934 |
| CHUK | RELA | ENSCAFP00000014093 | ENSCAFP00000019655 | Component of inhibitor of nuclear factor kappa B kinase complex. | RELA proto-oncogene, NF-kB subunit. | 0.998 |
| CHUK | RELB | ENSCAFP00000014093 | ENSCAFP00000006862 | Component of inhibitor of nuclear factor kappa B kinase complex. | RELB proto-oncogene, NF-kB subunit. | 0.982 |
| CHUK | TBK1 | ENSCAFP00000014093 | ENSCAFP00000049327 | Component of inhibitor of nuclear factor kappa B kinase complex. | TANK binding kinase 1. | 0.484 |
| CHUK | TNF | ENSCAFP00000014093 | ENSCAFP00000000739 | Component of inhibitor of nuclear factor kappa B kinase complex. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.982 |
| NFKB1 | CHUK | ENSCAFP00000056706 | ENSCAFP00000014093 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | Component of inhibitor of nuclear factor kappa B kinase complex. | 0.997 |
| NFKB1 | NFKB2 | ENSCAFP00000056706 | ENSCAFP00000014918 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | Nuclear factor kappa B subunit 2. | 0.996 |
| NFKB1 | NFKBIA | ENSCAFP00000056706 | ENSCAFP00000019772 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | NFKB inhibitor alpha. | 0.996 |
| NFKB1 | NFKBIB | ENSCAFP00000056706 | ENSCAFP00000042141 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | NFKB inhibitor beta. | 0.992 |
| NFKB1 | NFKBIE | ENSCAFP00000056706 | ENSCAFP00000002917 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | ANK_REP_REGION domain-containing protein. | 0.986 |
| NFKB1 | REL | ENSCAFP00000056706 | ENSCAFP00000004425 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | REL proto-oncogene, NF-kB subunit. | 0.993 |
| NFKB1 | RELA | ENSCAFP00000056706 | ENSCAFP00000019655 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | RELA proto-oncogene, NF-kB subunit. | 0.996 |
| NFKB1 | RELB | ENSCAFP00000056706 | ENSCAFP00000006862 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | RELB proto-oncogene, NF-kB subunit. | 0.994 |
| NFKB1 | TBK1 | ENSCAFP00000056706 | ENSCAFP00000049327 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | TANK binding kinase 1. | 0.960 |
| NFKB1 | TNF | ENSCAFP00000056706 | ENSCAFP00000000739 | Nuclear factor NF-kappa-B p105 subunit; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dime [...] | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.991 |
