STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAP1Adenylyl cyclase-associated protein; Belongs to the CAP family. (475 aa)    
Predicted Functional Partners:
LCP1
Lymphocyte cytosolic protein 1.
   
 
 0.771
WDR1
WD repeat domain 1.
   
 
 0.707
PFN4
Profilin; Belongs to the profilin family.
   
 
 0.667
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
   0.663
CORO1A
Coronin; Belongs to the WD repeat coronin family.
   
 
 0.640
PFN1
Profilin; Belongs to the profilin family.
   
 
 0.623
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
    
   0.600
CAPZB
Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.595
TLR9
Twinfilin actin binding protein 2.
   
 
 0.590
TWF1
Twinfilin actin binding protein 1.
   
 
 0.590
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.