CPVL protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CPVL

Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family. (483 aa)

Predicted Functional Partners:

CNKSR3

0.798

CAPZB

0.758

MFSD6

0.740

FXR1

0.641

STK17A

0.629

CTSA

0.629

MAGT1

0.617

ECE1

0.617

TUSC3

0.617

TMTC2

0.615

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPZB	CPVL	ENSCAFP00000065479	ENSCAFP00000004492	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	0.758
CAPZB	CTSA	ENSCAFP00000065479	ENSCAFP00000014432	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.424
CNKSR3	CPVL	ENSCAFP00000065573	ENSCAFP00000004492	Uncharacterized protein.	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	0.798
CNKSR3	FXR1	ENSCAFP00000065573	ENSCAFP00000063380	Uncharacterized protein.	FMR1 autosomal homolog 1.	0.519
CPVL	CAPZB	ENSCAFP00000004492	ENSCAFP00000065479	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.758
CPVL	CNKSR3	ENSCAFP00000004492	ENSCAFP00000065573	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Uncharacterized protein.	0.798
CPVL	CTSA	ENSCAFP00000004492	ENSCAFP00000014432	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.629
CPVL	ECE1	ENSCAFP00000004492	ENSCAFP00000048128	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Endothelin converting enzyme 1.	0.617
CPVL	FXR1	ENSCAFP00000004492	ENSCAFP00000063380	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	FMR1 autosomal homolog 1.	0.641
CPVL	MAGT1	ENSCAFP00000004492	ENSCAFP00000041043	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Magnesium transporter 1.	0.617
CPVL	MFSD6	ENSCAFP00000004492	ENSCAFP00000013945	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Major facilitator superfamily domain containing 6.	0.740
CPVL	STK17A	ENSCAFP00000004492	ENSCAFP00000005183	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Serine/threonine kinase 17a.	0.629
CPVL	TMTC2	ENSCAFP00000004492	ENSCAFP00000048460	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Transmembrane O-mannosyltransferase targeting cadherins 2.	0.615
CPVL	TUSC3	ENSCAFP00000004492	ENSCAFP00000061918	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	Tumor suppressor candidate 3.	0.617
CTSA	CAPZB	ENSCAFP00000014432	ENSCAFP00000065479	Carboxypeptidase; Belongs to the peptidase S10 family.	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.424
CTSA	CPVL	ENSCAFP00000014432	ENSCAFP00000004492	Carboxypeptidase; Belongs to the peptidase S10 family.	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	0.629
CTSA	MAGT1	ENSCAFP00000014432	ENSCAFP00000041043	Carboxypeptidase; Belongs to the peptidase S10 family.	Magnesium transporter 1.	0.447
CTSA	TUSC3	ENSCAFP00000014432	ENSCAFP00000061918	Carboxypeptidase; Belongs to the peptidase S10 family.	Tumor suppressor candidate 3.	0.447
ECE1	CPVL	ENSCAFP00000048128	ENSCAFP00000004492	Endothelin converting enzyme 1.	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.	0.617
FXR1	CNKSR3	ENSCAFP00000063380	ENSCAFP00000065573	FMR1 autosomal homolog 1.	Uncharacterized protein.	0.519