XPO1 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

XPO1

Exportin 1. (1071 aa)

Predicted Functional Partners:

CSE1L

0.996

XPO7

0.988

NUP214

0.987

RANBP17

0.973

RANBP2

0.971

RAN

0.965

LOC100686305

0.965

SNUPN

0.963

XPOT

0.954

XPO4

0.952

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSE1L	LOC100686305	ENSCAFP00000056901	ENSCAFP00000048537	Chromosome segregation 1 like.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.673
CSE1L	RAN	ENSCAFP00000056901	ENSCAFP00000009963	Chromosome segregation 1 like.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.673
CSE1L	RANBP17	ENSCAFP00000056901	ENSCAFP00000035834	Chromosome segregation 1 like.	RAN binding protein 17.	0.935
CSE1L	RANBP2	ENSCAFP00000056901	ENSCAFP00000062218	Chromosome segregation 1 like.	RAN binding protein 2.	0.767
CSE1L	XPO1	ENSCAFP00000056901	ENSCAFP00000004579	Chromosome segregation 1 like.	Exportin 1.	0.996
CSE1L	XPO4	ENSCAFP00000056901	ENSCAFP00000041949	Chromosome segregation 1 like.	Exportin 4.	0.952
CSE1L	XPO7	ENSCAFP00000056901	ENSCAFP00000041056	Chromosome segregation 1 like.	Exportin 7.	0.941
CSE1L	XPOT	ENSCAFP00000056901	ENSCAFP00000000504	Chromosome segregation 1 like.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.960
LOC100686305	CSE1L	ENSCAFP00000048537	ENSCAFP00000056901	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Chromosome segregation 1 like.	0.673
LOC100686305	NUP214	ENSCAFP00000048537	ENSCAFP00000029512	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Nucleoporin 214.	0.684
LOC100686305	RANBP2	ENSCAFP00000048537	ENSCAFP00000062218	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	RAN binding protein 2.	0.865
LOC100686305	SNUPN	ENSCAFP00000048537	ENSCAFP00000026649	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family.	0.807
LOC100686305	XPO1	ENSCAFP00000048537	ENSCAFP00000004579	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin 1.	0.965
LOC100686305	XPO4	ENSCAFP00000048537	ENSCAFP00000041949	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin 4.	0.588
LOC100686305	XPO7	ENSCAFP00000048537	ENSCAFP00000041056	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin 7.	0.513
LOC100686305	XPOT	ENSCAFP00000048537	ENSCAFP00000000504	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.828
NUP214	LOC100686305	ENSCAFP00000029512	ENSCAFP00000048537	Nucleoporin 214.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.684
NUP214	RAN	ENSCAFP00000029512	ENSCAFP00000009963	Nucleoporin 214.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.734
NUP214	RANBP2	ENSCAFP00000029512	ENSCAFP00000062218	Nucleoporin 214.	RAN binding protein 2.	0.977
NUP214	SNUPN	ENSCAFP00000029512	ENSCAFP00000026649	Nucleoporin 214.	Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family.	0.605