STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPACA1Sperm acrosome associated 1. (299 aa)    
Predicted Functional Partners:
SSMEM1
Serine rich single-pass membrane protein 1.
      
 0.923
CCDC62
Coiled-coil domain containing 62.
      
 0.853
ZPBP
Zona pellucida binding protein.
   
  
 0.843
SPATA16
Spermatogenesis associated 16.
   
  
 0.820
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 
 0.792
DPY19L2
Dpy-19 like 2.
   
  
 0.789
ANAPC16
Anaphase promoting complex subunit 16.
      
 0.782
TSSK4
Testis specific serine kinase 4.
    
 
 0.744
HIPK4
Homeodomain interacting protein kinase 4.
      
 0.740
SPACA3
Sperm acrosome membrane-associated protein 3; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N- acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity).
      
 0.707
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.