STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPACA1Sperm acrosome associated 1. (299 aa)    
Predicted Functional Partners:
ZPBP
Zona pellucida binding protein.
   
  
 0.853
SPACA6
Sperm acrosome associated 6.
      
 0.823
SPACA4
Sperm acrosome associated 4.
   
  
 0.812
ANAPC16
Anaphase promoting complex subunit 16.
      
 0.810
DPY19L2
Dpy-19 like 2.
   
  
 0.781
CCDC62
Coiled-coil domain containing 62.
      
 0.760
SSMEM1
Serine rich single-pass membrane protein 1.
      
 0.745
SPACA3
Sperm acrosome membrane-associated protein 3; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N- acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity).
   
  
 0.728
SPACA9
Sperm acrosome associated 9.
      
 0.726
MAPK1IP1L
Mitogen-activated protein kinase 1 interacting protein 1 like.
      
 0.711
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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