STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MINDY4MINDY lysine 48 deubiquitinase 4. (767 aa)    
Predicted Functional Partners:
GIT2
GIT ArfGAP 2.
      
 0.637
LRBA
LPS responsive beige-like anchor protein.
      
 0.620
MINDY1
MINDY lysine 48 deubiquitinase 1.
      
 0.517
PPP1R42
Protein phosphatase 1 regulatory subunit 42.
    
 
 0.501
CREM
cAMP-responsive element modulator; Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Tau is a transcriptional activator. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity).
      
 0.497
TTC22
Tetratricopeptide repeat domain 22.
      
 0.495
FAM228B
Uncharacterized protein.
      
 0.495
TOX2
TOX high mobility group box family member 2.
      
 0.485
MINDY2
MINDY lysine 48 deubiquitinase 2.
      
 0.450
CDC42BPA
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
  
 0.426
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.