STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBRG4Transforming growth factor beta regulator 4. (631 aa)    
Predicted Functional Partners:
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
    
 
 0.703
TOMM40
Translocase of outer mitochondrial membrane 40.
   
    0.700
RAMP3
Receptor activity modifying protein 3.
   
  
 0.673
SUPV3L1
Suv3 like RNA helicase.
   
  
 0.668
CYC1
Cytochrome c1.
   
    0.663
LYPD3
LY6/PLAUR domain containing 3.
    
 
 0.656
STXBP2
Syntaxin-binding protein 2; Involved in the protein trafficking from the Golgi apparatus to the plasma membrane; Belongs to the STXBP/unc-18/SEC1 family.
   
  
 0.607
AP1B1
AP complex subunit beta.
   
 
 0.590
AP2B1
AP complex subunit beta.
   
 
 0.583
DHX30
DExH-box helicase 30.
   
 
 0.579
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.