Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RP9RP9 pre-mRNA splicing factor. (220 aa)    
Predicted Functional Partners:
PRPF3
Pre-mRNA processing factor 3.
      
 0.885
PRPF31
Nop domain-containing protein.
   
  
 0.844
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
      
 0.828
PRPF8
Pre-mRNA processing factor 8.
      
 0.793
PRPF4
Pre-mRNA processing factor 4.
      
 0.752
TOPORS
TOP1 binding arginine/serine rich protein.
   
  
 0.676
PRPF6
Pre-mRNA processing factor 6.
      
 0.671
PRPH2
Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). Belongs to the PRPH2/ROM1 family.
      
 0.660
NKAP
NFKB activating protein.
   
 
 0.638
ROM1
Retinal outer segment membrane protein 1.
      
 0.631
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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