STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL2Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (303 aa)    
Predicted Functional Partners:
PARL
Presenilin associated rhomboid like.
   
  
 0.684
CLEC14A
C-type lectin domain containing 14A.
    
 
 0.680
STOML3
Stomatin like 3.
   
 
 0.673
GSTCD
Glutathione S-transferase C-terminal domain containing.
   
  
 0.672
KLC3
Kinesin light chain 3.
   
  
 0.651
DENND1B
DENN domain containing 1B.
      
 0.642
WDR5B
WD repeat domain 5B.
      
 0.641
ZNF710
Zinc finger protein 710.
   
  
 0.637
ROM1
Retinal outer segment membrane protein 1.
   
  
 0.579
RHBDD3
Rhomboid domain containing 3.
   
  
 0.566
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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