STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3YL1SH3 and SYLF domain containing 1. (342 aa)    
Predicted Functional Partners:
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
   0.813
WAS
WASP actin nucleation promoting factor.
    
 
 0.757
WASL
WASP like actin nucleation promoting factor.
    
 
 0.757
NBR1
NBR1 autophagy cargo receptor.
   
  
 0.652
SH3D19
SH3 domain containing 19.
   
  
0.615
RAB12
Uncharacterized protein.
      
 0.562
ANKRD54
Ankyrin repeat domain 54.
    
 
 0.559
A2ML1
Alpha-2-macroglobulin like 1.
   
  
 0.555
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein.
      
 0.550
PI3
Trappin-2.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.