STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDHD3Haloacid dehalogenase like hydrolase domain containing 3. (251 aa)    
Predicted Functional Partners:
FGFBP3
Fibroblast growth factor binding protein 3.
      
 0.816
NDRG3
NDRG family member 3.
   
 
 0.816
B4GALT3
Beta-1,4-galactosyltransferase 3.
   
  
 0.787
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
   
 
 0.717
PSAT1
Phosphoserine aminotransferase.
   
 
 0.713
GRID2
Glutamate ionotropic receptor delta type subunit 2.
      
 0.680
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.566
TSPEAR
Thrombospondin type laminin G domain and EAR repeats.
      
 0.562
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
     
 0.561
MTAP
Methylthioadenosine phosphorylase.
  
 
 0.554
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.