STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)    
Predicted Functional Partners:
HMBS
Hydroxymethylbilane synthase.
 
 0.999
UROS
Uroporphyrinogen III synthase.
  
 0.997
ALAS1
5'-aminolevulinate synthase 1.
  
 
 0.983
ALAS2
5-aminolevulinate synthase.
  
 
 0.973
UROD
Uroporphyrinogen decarboxylase.
  
 
 0.952
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.911
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.864
CPOX
Coproporphyrinogen oxidase.
  
  
 0.853
DBI
Acyl-CoA-binding protein.
   
  
 0.798
EPB41L4A
Erythrocyte membrane protein band 4.1 like 4A.
      
 0.791
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.