STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)    
Predicted Functional Partners:
HMBS
Hydroxymethylbilane synthase.
 
 0.997
UROS
Uroporphyrinogen III synthase.
  
 0.995
ALAS1
5'-aminolevulinate synthase 1.
    
 0.968
UROD
Uroporphyrinogen decarboxylase.
  
 
 0.960
ALAS2
5-aminolevulinate synthase.
  
 
 0.936
CPOX
Coproporphyrinogen oxidase.
  
 
 0.919
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.909
PPOX
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.833
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.825
EPB41L4A
Erythrocyte membrane protein band 4.1 like 4A.
      
 0.821
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.