STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C11H9orf43Chromosome 11 C9orf43 homolog. (580 aa)    
Predicted Functional Partners:
BSPRY
B-box and SPRY domain containing.
      
 0.495
NIF3L1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
      
 0.489
HDHD3
Haloacid dehalogenase like hydrolase domain containing 3.
      
 0.481
CDC26
Cell division cycle 26.
      
 0.450
SGO2
Shugoshin 2.
      
 0.450
SLC31A2
Solute carrier family 31 member 2.
      
 0.432
SLC31A1
Solute carrier family 31 member 1.
      
 0.420
ENSCAFP00000046206
Uncharacterized protein.
      
 0.400
EMC8
ER membrane protein complex subunit 8.
      
 0.400
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.