STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTF1Metal regulatory transcription factor 1. (873 aa)    
Predicted Functional Partners:
NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2.
   
  
 0.674
MT1E
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
   
  
 0.576
ATP7B
ATPase copper transporting beta.
    
 
 0.569
CYP7B1
Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 
 0.569
MT4
Metallothionein-4; Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia (By similarity).
   
  
 0.564
TP53I3
Tumor protein p53 inducible protein 3.
    
 
 0.530
HSF1
Heat shock transcription factor 1.
   
 
 0.522
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
  
 0.519
SCYL1
SCY1 like pseudokinase 1.
      
 0.515
SLC30A9
Solute carrier family 30 member 9.
      
 0.509
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.