STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP25Rho-GAP domain-containing protein. (338 aa)    
Predicted Functional Partners:
STK32A
Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.
      
 0.832
DENND1A
DENN domain containing 1A.
   
  
 0.655
NANOS1
Nanos-type domain-containing protein; Belongs to the nanos family.
      
 0.618
ATAT1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
      
 0.591
SKOR2
c-SKI_SMAD_bind domain-containing protein.
      
 0.591
WAS
WASP actin nucleation promoting factor.
   
   0.589
SALL2
Spalt like transcription factor 2.
      
 0.582
DNAH2
Dynein axonemal heavy chain 2.
      
 0.533
JMJD1C
Jumonji domain containing 1C.
   
  
 0.527
DPYSL3
Dihydropyrimidinase like 3.
      
 0.519
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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