RSPO1 protein (Canis lupus familiaris) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

RSPO1

R-spondin 1. (263 aa)

Predicted Functional Partners:

LGR4

0.997

LGR5

0.997

RNF43

0.994

LGR6

0.960

ZNRF3

0.949

RSPO3

0.908

RSPO2

0.906

WNT4

0.880

SOX3

0.807

EGF

0.772

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	LGR5	ENSCAFP00000016954	ENSCAFP00000066431	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Leucine rich repeat containing G protein-coupled receptor 5.	0.624
EGF	RSPO1	ENSCAFP00000016954	ENSCAFP00000004870	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	R-spondin 1.	0.772
EGF	SOX3	ENSCAFP00000016954	ENSCAFP00000028081	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	SRY-box 3.	0.465
LGR4	LGR5	ENSCAFP00000053802	ENSCAFP00000066431	Leucine rich repeat containing G protein-coupled receptor 4.	Leucine rich repeat containing G protein-coupled receptor 5.	0.925
LGR4	LGR6	ENSCAFP00000053802	ENSCAFP00000015480	Leucine rich repeat containing G protein-coupled receptor 4.	Leucine rich repeat containing G protein-coupled receptor 6.	0.931
LGR4	RNF43	ENSCAFP00000053802	ENSCAFP00000025813	Leucine rich repeat containing G protein-coupled receptor 4.	Ring finger protein 43.	0.971
LGR4	RSPO1	ENSCAFP00000053802	ENSCAFP00000004870	Leucine rich repeat containing G protein-coupled receptor 4.	R-spondin 1.	0.997
LGR4	RSPO2	ENSCAFP00000053802	ENSCAFP00000051446	Leucine rich repeat containing G protein-coupled receptor 4.	R-spondin 2.	0.995
LGR4	RSPO3	ENSCAFP00000053802	ENSCAFP00000001500	Leucine rich repeat containing G protein-coupled receptor 4.	R-spondin 3.	0.974
LGR4	ZNRF3	ENSCAFP00000053802	ENSCAFP00000017623	Leucine rich repeat containing G protein-coupled receptor 4.	Zinc and ring finger 3.	0.875
LGR5	EGF	ENSCAFP00000066431	ENSCAFP00000016954	Leucine rich repeat containing G protein-coupled receptor 5.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.624
LGR5	LGR4	ENSCAFP00000066431	ENSCAFP00000053802	Leucine rich repeat containing G protein-coupled receptor 5.	Leucine rich repeat containing G protein-coupled receptor 4.	0.925
LGR5	LGR6	ENSCAFP00000066431	ENSCAFP00000015480	Leucine rich repeat containing G protein-coupled receptor 5.	Leucine rich repeat containing G protein-coupled receptor 6.	0.916
LGR5	RNF43	ENSCAFP00000066431	ENSCAFP00000025813	Leucine rich repeat containing G protein-coupled receptor 5.	Ring finger protein 43.	0.944
LGR5	RSPO1	ENSCAFP00000066431	ENSCAFP00000004870	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 1.	0.997
LGR5	RSPO2	ENSCAFP00000066431	ENSCAFP00000051446	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 2.	0.992
LGR5	RSPO3	ENSCAFP00000066431	ENSCAFP00000001500	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 3.	0.970
LGR5	WNT4	ENSCAFP00000066431	ENSCAFP00000050650	Leucine rich repeat containing G protein-coupled receptor 5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.563
LGR5	ZNRF3	ENSCAFP00000066431	ENSCAFP00000017623	Leucine rich repeat containing G protein-coupled receptor 5.	Zinc and ring finger 3.	0.571
LGR6	LGR4	ENSCAFP00000015480	ENSCAFP00000053802	Leucine rich repeat containing G protein-coupled receptor 6.	Leucine rich repeat containing G protein-coupled receptor 4.	0.931