STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSAD2Radical S-adenosyl methionine domain containing 2. (361 aa)    
Predicted Functional Partners:
IFI44
Interferon induced protein 44.
   
  
 0.961
USP18
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
  
 0.950
ISG15
ISG15 ubiquitin like modifier.
   
  
 0.942
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.936
MX1
Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).
   
  
 0.926
DDX58
DExD/H-box helicase 58.
   
  
 0.920
OASL
2'-5' oligoadenylate synthetase-like 1.
   
  
 0.891
IFIT1
Interferon induced protein with tetratricopeptide repeats 1.
   
 
 0.876
EIF2AK2
Eukaryotic translation initiation factor 2-alpha kinase 2.
   
  
 0.863
STAT1
Signal transducer and activator of transcription.
   
  
 0.858
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.