STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM168Transmembrane protein 168. (649 aa)    
Predicted Functional Partners:
OGFOD2
2-oxoglutarate and iron dependent oxygenase domain containing 2.
      
 0.794
TMEM98
Transmembrane protein 98.
      
 0.658
TMEM45B
Transmembrane protein 45B.
      
 0.629
ADPRH
ADP-ribosylarginine hydrolase.
      
 0.629
TMEM170B
Transmembrane protein 170B.
   
  
 0.629
TMEM45A
Transmembrane protein 45A.
      
 0.622
TMEM88
Transmembrane protein 88.
      
 0.616
CAPZA3
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
  
 0.604
FRAT2
FRAT regulator of WNT signaling pathway 2.
      
 0.591
FAM13A
Family with sequence similarity 13 member A.
      
 0.587
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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