STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIDINS220Kinase D interacting substrate 220. (1772 aa)    
Predicted Functional Partners:
CRKL
CRK like proto-oncogene, adaptor protein.
   
 0.931
CRK
CRK proto-oncogene, adaptor protein.
    
 0.921
TUBGCP6
Tubulin gamma complex associated protein 6.
    
 
 0.865
TBC1D24
Uncharacterized protein.
   
 
 0.813
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
   0.719
FKBP15
Peptidylprolyl isomerase.
   
 
 0.716
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
    
 
 0.692
BPTF
Bromodomain PHD finger transcription factor.
   
  
 0.673
PRKD3
Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
   
 
 0.611
RND1
Rho family GTPase 1.
   
 0.601
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.