STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM268Transmembrane protein 268. (345 aa)    
Predicted Functional Partners:
TMEM266
Transmembrane protein 266.
      
 0.684
KATNB1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...]
      
 0.610
CDK14
Cyclin dependent kinase 14; Belongs to the protein kinase superfamily.
      
 0.610
MRC2
Mannose receptor C type 2.
      
 0.569
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
      
 0.559
SLC35F4
Solute carrier family 35 member F4.
      
 0.539
SLC3A2
Aamy domain-containing protein.
      
 0.473
GTPBP2
GTP binding protein 2.
      
 0.465
KCNE4
Potassium voltage-gated channel subfamily E regulatory subunit 4.
      
 0.459
ILDR1
Immunoglobulin like domain containing receptor 1.
      
 0.455
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (12%) [HD]