TNFSF8 protein (Canis lupus familiaris) - STRING interaction network

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Score

TNFSF8

Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (234 aa)

Predicted Functional Partners:

TNFRSF8

0.999

MIIP

0.792

TNFRSF1B

0.770

TNFSF15

0.667

TNFSF9

0.651

TNFRSF25

0.596

CD47

0.524

TMEM140

0.519

CD40LG

0.509

PROCR

0.503

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40LG	CD47	ENSCAFP00000027967	ENSCAFP00000060446	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	CD47 molecule.	0.402
CD40LG	TNFSF8	ENSCAFP00000027967	ENSCAFP00000005002	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.509
CD40LG	TNFSF9	ENSCAFP00000027967	ENSCAFP00000042006	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	TNF superfamily member 9; Belongs to the tumor necrosis factor family.	0.473
CD47	CD40LG	ENSCAFP00000060446	ENSCAFP00000027967	CD47 molecule.	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	0.402
CD47	PROCR	ENSCAFP00000060446	ENSCAFP00000052069	CD47 molecule.	MHC_I-like_Ag-recog domain-containing protein.	0.478
CD47	TNFSF8	ENSCAFP00000060446	ENSCAFP00000005002	CD47 molecule.	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.524
MIIP	TNFRSF1B	ENSCAFP00000036463	ENSCAFP00000053688	Migration and invasion inhibitory protein.	TNF receptor superfamily member 1B.	0.411
MIIP	TNFRSF8	ENSCAFP00000036463	ENSCAFP00000024179	Migration and invasion inhibitory protein.	TNF receptor superfamily member 8.	0.734
MIIP	TNFSF8	ENSCAFP00000036463	ENSCAFP00000005002	Migration and invasion inhibitory protein.	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.792
PROCR	CD47	ENSCAFP00000052069	ENSCAFP00000060446	MHC_I-like_Ag-recog domain-containing protein.	CD47 molecule.	0.478
PROCR	TNFSF8	ENSCAFP00000052069	ENSCAFP00000005002	MHC_I-like_Ag-recog domain-containing protein.	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.503
TMEM140	TNFSF8	ENSCAFP00000052308	ENSCAFP00000005002	Transmembrane protein 140.	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.519
TNFRSF1B	MIIP	ENSCAFP00000053688	ENSCAFP00000036463	TNF receptor superfamily member 1B.	Migration and invasion inhibitory protein.	0.411
TNFRSF1B	TNFRSF25	ENSCAFP00000053688	ENSCAFP00000053085	TNF receptor superfamily member 1B.	TNF receptor superfamily member 25.	0.716
TNFRSF1B	TNFSF15	ENSCAFP00000053688	ENSCAFP00000039597	TNF receptor superfamily member 1B.	TNF superfamily member 15.	0.621
TNFRSF1B	TNFSF8	ENSCAFP00000053688	ENSCAFP00000005002	TNF receptor superfamily member 1B.	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.770
TNFRSF25	TNFRSF1B	ENSCAFP00000053085	ENSCAFP00000053688	TNF receptor superfamily member 25.	TNF receptor superfamily member 1B.	0.716
TNFRSF25	TNFRSF8	ENSCAFP00000053085	ENSCAFP00000024179	TNF receptor superfamily member 25.	TNF receptor superfamily member 8.	0.515
TNFRSF25	TNFSF15	ENSCAFP00000053085	ENSCAFP00000039597	TNF receptor superfamily member 25.	TNF superfamily member 15.	0.987
TNFRSF25	TNFSF8	ENSCAFP00000053085	ENSCAFP00000005002	TNF receptor superfamily member 25.	Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family.	0.596