STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF8Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (234 aa)    
Predicted Functional Partners:
TNFRSF8
TNF receptor superfamily member 8.
    
 0.951
TNFSF9
TNF superfamily member 9; Belongs to the tumor necrosis factor family.
   
 
 0.691
TNFSF15
TNF superfamily member 15.
   
  
 0.688
TNFRSF25
TNF receptor superfamily member 25.
   
  
 0.610
TNFRSF9
TNF receptor superfamily member 9.
   
  
 0.576
DIABLO
Diablo IAP-binding mitochondrial protein.
   
  
 0.561
PROCR
MHC_I-like_Ag-recog domain-containing protein.
  
    0.503
CD47
CD47 molecule.
  
    0.497
IRF5
Interferon regulatory factor 5.
   
  
 0.488
KITLG
Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins.
  
     0.488
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.