STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK40Serine/threonine kinase 40. (470 aa)    
Predicted Functional Partners:
COP1
COP1 E3 ubiquitin ligase.
   
 
 0.736
KPNA6
Importin subunit alpha; Functions in nuclear protein import.
   
  
 0.710
VAC14
VAC14 component of PIKFYVE complex.
   
 
 0.688
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4.
   
 
 0.684
CTC1
CST telomere replication complex component 1.
      
 0.681
YARS1
Tyrosine--tRNA ligase.
   
  
 0.680
USP33
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.675
TRIB1
Protein kinase domain-containing protein.
   
 
0.668
NLE1
Notchless homolog 1.
   
  
 0.644
CHEK2
Tetratricopeptide repeat domain 28.
    
 
 0.631
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.