DDC protein (Canis lupus familiaris) - STRING interaction network

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Score

DDC

Dopa decarboxylase. (506 aa)

Predicted Functional Partners:

TH

0.979

COMT

0.969

LOC106560171

0.960

MAOA

0.960

MAOB

0.957

DBH

0.953

IDO1

0.947

TPH1

0.944

TDO2

0.941

PAH

0.939

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COMT	DBH	ENSCAFP00000021031	ENSCAFP00000029281	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	0.960
COMT	DDC	ENSCAFP00000021031	ENSCAFP00000005077	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Dopa decarboxylase.	0.969
COMT	LOC106560171	ENSCAFP00000021031	ENSCAFP00000008652	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Uncharacterized protein.	0.934
COMT	MAOA	ENSCAFP00000021031	ENSCAFP00000021307	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).	0.984
COMT	MAOB	ENSCAFP00000021031	ENSCAFP00000021330	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).	0.984
COMT	TH	ENSCAFP00000021031	ENSCAFP00000014845	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons.	0.707
DBH	COMT	ENSCAFP00000029281	ENSCAFP00000021031	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	0.960
DBH	DDC	ENSCAFP00000029281	ENSCAFP00000005077	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Dopa decarboxylase.	0.953
DBH	LOC106560171	ENSCAFP00000029281	ENSCAFP00000008652	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Uncharacterized protein.	0.939
DBH	MAOA	ENSCAFP00000029281	ENSCAFP00000021307	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).	0.953
DBH	MAOB	ENSCAFP00000029281	ENSCAFP00000021330	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).	0.959
DBH	PAH	ENSCAFP00000029281	ENSCAFP00000010860	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Phenylalanine hydroxylase.	0.800
DBH	TH	ENSCAFP00000029281	ENSCAFP00000014845	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons.	0.947
DDC	COMT	ENSCAFP00000005077	ENSCAFP00000021031	Dopa decarboxylase.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	0.969
DDC	DBH	ENSCAFP00000005077	ENSCAFP00000029281	Dopa decarboxylase.	Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline.	0.953
DDC	IDO1	ENSCAFP00000005077	ENSCAFP00000062598	Dopa decarboxylase.	Indoleamine 2,3-dioxygenase 1.	0.947
DDC	LOC106560171	ENSCAFP00000005077	ENSCAFP00000008652	Dopa decarboxylase.	Uncharacterized protein.	0.960
DDC	MAOA	ENSCAFP00000005077	ENSCAFP00000021307	Dopa decarboxylase.	Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).	0.960
DDC	MAOB	ENSCAFP00000005077	ENSCAFP00000021330	Dopa decarboxylase.	Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).	0.957
DDC	PAH	ENSCAFP00000005077	ENSCAFP00000010860	Dopa decarboxylase.	Phenylalanine hydroxylase.	0.939