STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VRK3VRK serine/threonine kinase 3. (455 aa)    
Predicted Functional Partners:
DUSP3
Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 0.932
FAM83H
Family with sequence similarity 83 member H.
    
 
 0.819
PNKP
Polynucleotide kinase 3'-phosphatase.
   
  
 0.658
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 
 0.649
LTV1
LTV1 ribosome biogenesis factor.
    
 
 0.639
FAM83C
Family with sequence similarity 83 member C.
    
 
 0.591
FAM83E
Family with sequence similarity 83 member E.
   
 
 0.575
FAM83B
Family with sequence similarity 83 member B.
    
 
 0.567
ENSCAFP00000050943
Uncharacterized protein.
    
 
 0.567
BYSL
Bystin like.
    
 
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.