STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL1Cullin 1; Belongs to the cullin family. (776 aa)    
Predicted Functional Partners:
FBXW11
F-box and WD repeat domain containing 11.
   
 0.999
RBX1
Ring-box 1.
    
 0.999
SKP2
S-phase kinase associated protein 2.
    
 0.997
FBXL3
F-box and leucine rich repeat protein 3.
   
 0.996
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.996
FBXO5
F-box protein 5.
    
 0.992
ENSCAFP00000063226
Uncharacterized protein; Belongs to the SKP1 family.
   
 0.992
FBXL5
F-box and leucine rich repeat protein 5.
    
 0.991
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.990
NFKBIA
NFKB inhibitor alpha.
   
 0.990
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.