POU3F3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

POU3F3

POU domain protein. (372 aa)

Predicted Functional Partners:

NOL11

0.602

CSRNP3

0.595

IYD

0.591

POU3F4

0.573

MNX1

0.565

POU4F3

0.528

KCNH8

0.526

DPH1

0.524

C5H11orf53

0.520

POU4F2

0.519

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5H11orf53	POU3F3	ENSCAFP00000041365	ENSCAFP00000005157	Chromosome 5 C11orf53 homolog.	POU domain protein.	0.520
C5H11orf53	POU3F4	ENSCAFP00000041365	ENSCAFP00000025584	Chromosome 5 C11orf53 homolog.	POU domain protein.	0.520
CSRNP3	DPH1	ENSCAFP00000038496	ENSCAFP00000036004	Cysteine and serine rich nuclear protein 3.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.592
CSRNP3	KCNH8	ENSCAFP00000038496	ENSCAFP00000008722	Cysteine and serine rich nuclear protein 3.	Potassium voltage-gated channel subfamily H member 8.	0.592
CSRNP3	POU3F3	ENSCAFP00000038496	ENSCAFP00000005157	Cysteine and serine rich nuclear protein 3.	POU domain protein.	0.595
DPH1	CSRNP3	ENSCAFP00000036004	ENSCAFP00000038496	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Cysteine and serine rich nuclear protein 3.	0.592
DPH1	KCNH8	ENSCAFP00000036004	ENSCAFP00000008722	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Potassium voltage-gated channel subfamily H member 8.	0.489
DPH1	POU3F3	ENSCAFP00000036004	ENSCAFP00000005157	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	POU domain protein.	0.524
IYD	POU3F3	ENSCAFP00000000578	ENSCAFP00000005157	Iodotyrosine deiodinase.	POU domain protein.	0.591
KCNH8	CSRNP3	ENSCAFP00000008722	ENSCAFP00000038496	Potassium voltage-gated channel subfamily H member 8.	Cysteine and serine rich nuclear protein 3.	0.592
KCNH8	DPH1	ENSCAFP00000008722	ENSCAFP00000036004	Potassium voltage-gated channel subfamily H member 8.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.489
KCNH8	POU3F3	ENSCAFP00000008722	ENSCAFP00000005157	Potassium voltage-gated channel subfamily H member 8.	POU domain protein.	0.526
MNX1	POU3F3	ENSCAFP00000007681	ENSCAFP00000005157	Motor neuron and pancreas homeobox 1.	POU domain protein.	0.565
NOL11	POU3F3	ENSCAFP00000016921	ENSCAFP00000005157	Nucleolar protein 11.	POU domain protein.	0.602
POU3F3	C5H11orf53	ENSCAFP00000005157	ENSCAFP00000041365	POU domain protein.	Chromosome 5 C11orf53 homolog.	0.520
POU3F3	CSRNP3	ENSCAFP00000005157	ENSCAFP00000038496	POU domain protein.	Cysteine and serine rich nuclear protein 3.	0.595
POU3F3	DPH1	ENSCAFP00000005157	ENSCAFP00000036004	POU domain protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.524
POU3F3	IYD	ENSCAFP00000005157	ENSCAFP00000000578	POU domain protein.	Iodotyrosine deiodinase.	0.591
POU3F3	KCNH8	ENSCAFP00000005157	ENSCAFP00000008722	POU domain protein.	Potassium voltage-gated channel subfamily H member 8.	0.526
POU3F3	MNX1	ENSCAFP00000005157	ENSCAFP00000007681	POU domain protein.	Motor neuron and pancreas homeobox 1.	0.565