STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNISRPNN interacting serine and arginine rich protein. (814 aa)    
Predicted Functional Partners:
PNN
Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...]
   
 
 0.909
LUC7L3
LUC7 like 3 pre-mRNA splicing factor.
   
  
 0.898
PRPF39
Pre-mRNA processing factor 39.
   
  
 0.894
SRSF11
Serine and arginine rich splicing factor 11.
   
 
 0.885
SREK1
Splicing regulatory glutamic acid and lysine rich protein 1.
   
 
 0.880
ZFC3H1
Zinc finger C3H1-type containing.
   
    0.852
TTC14
Tetratricopeptide repeat domain 14.
   
   0.835
FAXC
Failed axon connections homolog, metaxin like GST domain containing.
   
  
 0.804
NKTR
Natural killer cell triggering receptor.
  
   0.775
FBXL4
F-box and leucine rich repeat protein 4.
   
  
 0.751
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.