STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKT1S1AKT1 substrate 1. (276 aa)    
Predicted Functional Partners:
RPTOR
Regulatory associated protein of MTOR complex 1.
   
 0.997
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.993
MLST8
MTOR associated protein, LST8 homolog.
   
 0.988
DEPTOR
DEP domain containing MTOR interacting protein.
    
 0.985
EIF4EBP1
Eukaryotic translation initiation factor 4E binding protein 1.
   
 0.969
RRAGC
Ras related GTP binding C.
    
 0.951
RPS6KB2
Non-specific serine/threonine protein kinase.
   
 0.949
ULK1
Unc-51 like autophagy activating kinase 1.
   
 0.948
ATG13
Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.
   
 0.947
ALKAL1
RB1 inducible coiled-coil 1.
    
 0.944
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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