STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTSR2Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (379 aa)    
Predicted Functional Partners:
NTS
Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
    
 0.997
NTSR1
Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
  
0.932
NMU
Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family.
    
 0.862
GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
    
 0.825
GNA14
G protein subunit alpha 14.
    
 0.825
GNA15
G protein subunit alpha 15.
    
  0.775
NMUR2
Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
0.713
NDRG4
NDRG family member 4.
   
  
 0.682
GNA11
Uncharacterized protein.
    
 0.666
NMUR1
Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
0.608
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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