NTSR2 protein (Canis lupus familiaris) - STRING interaction network

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NTSR2

Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (379 aa)

Predicted Functional Partners:

NTS

0.978

COPA

0.700

NTSR1

0.627

NDRG4

0.627

GABRD

0.610

NPS

0.601

EDN1

0.569

EDN3

0.554

SLCO1C1

0.547

GNAQ

0.545

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPA	NTS	ENSCAFP00000018474	ENSCAFP00000008959	Coatomer subunit alpha; Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.677
COPA	NTSR1	ENSCAFP00000018474	ENSCAFP00000018703	Coatomer subunit alpha; Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor.	Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.874
COPA	NTSR2	ENSCAFP00000018474	ENSCAFP00000005334	Coatomer subunit alpha; Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor.	Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.700
EDN1	EDN3	ENSCAFP00000014389	ENSCAFP00000018044	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	0.938
EDN1	GNAQ	ENSCAFP00000014389	ENSCAFP00000028446	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.585
EDN1	NPS	ENSCAFP00000014389	ENSCAFP00000040359	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuropeptide S.	0.400
EDN1	NTS	ENSCAFP00000014389	ENSCAFP00000008959	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.607
EDN1	NTSR1	ENSCAFP00000014389	ENSCAFP00000018703	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.569
EDN1	NTSR2	ENSCAFP00000014389	ENSCAFP00000005334	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.569
EDN3	EDN1	ENSCAFP00000018044	ENSCAFP00000014389	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.938
EDN3	GNAQ	ENSCAFP00000018044	ENSCAFP00000028446	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	0.618
EDN3	NPS	ENSCAFP00000018044	ENSCAFP00000040359	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	Neuropeptide S.	0.400
EDN3	NTS	ENSCAFP00000018044	ENSCAFP00000008959	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.417
EDN3	NTSR1	ENSCAFP00000018044	ENSCAFP00000018703	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.555
EDN3	NTSR2	ENSCAFP00000018044	ENSCAFP00000005334	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.554
GABRD	NTSR2	ENSCAFP00000028625	ENSCAFP00000005334	Gamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.610
GNAQ	EDN1	ENSCAFP00000028446	ENSCAFP00000014389	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.585
GNAQ	EDN3	ENSCAFP00000028446	ENSCAFP00000018044	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides.	0.618
GNAQ	NPS	ENSCAFP00000028446	ENSCAFP00000040359	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Neuropeptide S.	0.509
GNAQ	NTS	ENSCAFP00000028446	ENSCAFP00000008959	Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.536