STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRRG2Proline rich and Gla domain 2. (202 aa)    
Predicted Functional Partners:
GGCX
Gamma-glutamyl carboxylase.
    
 
 0.898
RCN3
Reticulocalbin 3.
      
 0.881
PRR12
Proline rich 12.
 
    
 0.863
NOSIP
Nitric oxide synthase interacting protein.
      
 0.801
LRRC20
Leucine rich repeat containing 20.
      
 0.800
WWTR1
WW domain containing transcription regulator 1.
    
 
 0.713
YAP1
Yes associated protein 1.
    
 
 0.713
SHISA4
Uncharacterized protein.
      
 0.692
SCGN
Secretagogin, EF-hand calcium binding protein.
      
 0.607
CDON
Cell adhesion associated, oncogene regulated.
      
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.